**Please be advised that due to a fire next door on January 2nd, the pharmacy has TEMPORARILY moved to:
155 SE 2nd Main St Hillsboro, OR 97123
Thank you for your patience!**

Now offering Flu Shots. Walk-ins available!
We also offer "Monoclonal Antibodies" treatment for patients with Covid-19.
Hillsboro Pharmacy Logo

Get Healthy!

Prescription Fish Oil Pill Lowers Heart Attack Risk in Those Already on Statins
  • Posted March 18, 2019

Prescription Fish Oil Pill Lowers Heart Attack Risk in Those Already on Statins

MONDAY, March 18, 2019 (HealthDay News) -- Patients who have high triglycerides and take cholesterol-lowering statins to lower their risk for heart attack or stroke can cut that risk by another 30 percent by adding a high-dose omega-3 fatty acid pill, investigators report.

The prescription drug, called Vascepa, is not to be confused with over-the-counter dietary omega-3 (often fish oil) supplements. Such supplements typically contain far lower doses of the critical omega-3 fatty acid called EPA and have not undergone a rigorous safety and effectiveness review by the U.S. Food and Drug Administration.

Since 2012, the FDA has approved Vascepa (icosapent ethyl) for patients whose triglyceride fat levels exceed 500 milligrams per deciliter of blood.

Now, an updated analysis of research first released last September suggests Vascepa markedly reduces a patient's lifetime risk of dying from heart disease; experiencing a nonlethal heart attack or stroke, or needing heart surgery or hospitalization for a heart complication.

"We found a 30 percent reduction in total ischemic events," said lead author Dr. Deepak Bhatt, referring to any number of serious heart problems caused by restricted blood flow. "That is a very large degree of clinical benefit."

Among 1,000 patients who take Vascepa for five years, nearly 160 serious heart problems would be prevented, he noted. That includes 12 cardiovascular-related deaths, 42 heart attacks, 14 strokes, 76 coronary artery bypasses and 16 hospitalizations for unstable angina (chest pain or heaviness) while at rest or during moderate activity.

Bhatt is executive director of international cardiovascular programs at Brigham and Women's Hospital in Boston.

He and his colleagues are slated to present their research -- which was funded by the New Jersey-based drug manufacturer Amarin Pharma, Inc. -- this week at a meeting of the American College of Cardiology, in New Orleans.

Research presented at meetings is typically considered preliminary until published in a peer-reviewed journal.

The study team likened the high dose of EPA contained in Vascepa to eating more than 20 servings of fish a week, minus the problematic saturated fat.

The updated findings concern the "REDUCE-IT" study, which involved nearly 8,200 patients. All had high cholesterol and were taking statins to control it.

This, investigators said, meant patients were receiving a good standard of care. But that care did not mean they were out of the cardiac woods.

All also had high triglycerides, and about 70 percent had a heart disease diagnosis. The other 30 percent were diabetic and were thought to be at risk for future heart complications.

For the trial, half took 2 grams of Vascepa twice a day for an average of about five years. Half took a placebo.

Initial results suggested a 25 percent reduction in the risk for experiencing a first cardiac event, such as a heart attack or stroke.

Now, researchers have also examined subsequent events as well -- for example, a fatal stroke after an initial heart attack.

And that new analysis showed a 30 percent lower lifetime risk for heart attack, stroke and the like.

Eileen Handberg is research professor of medicine, and program director of the Cardiovascular Clinical Trials Program at the University of Florida. She was not involved with the study.

Handberg said the findings are important, because even when heart patients receive the very best of care, some risk remains. And patients with a risk for heart disease tend to experience more than one event -- meaning multiple heart attacks, or a heart attack and then a stroke, she added.

"But here, the data shows that this drug reduces that risk, whether it's a first, second or third event," Handberg said. "That is very important information for patients to have, because it means there is a way to reduce risk over the long term."

She underscored the research team's warning that consumers should not look to over-the-counter fish-oil supplements for the same protection.

"Supplements are not manufactured to consistent standards and are unregulated," Handberg said. "So you have no real idea of what you're taking."

More information

The U.S. Centers for Disease Control and Prevention offers more on heart disease.

SOURCES: Deepak Bhatt, M.D., M.P.H., executive director, Interventional Vardiovascular Programs, Brigham and Women's Hospital, Boston; Eileen Handberg, Ph.D., research professor, medicine, and program director, Cardiovascular Clinical Trials Program, University of Florida, Gainesville; American College of Cardiology meeting, New Orleans, March 16-18, 2019
HealthDay
Health News is provided as a service to Hillsboro Pharmacy site users by HealthDay. Hillsboro Pharmacy nor its employees, agents, or contractors, review, control, or take responsibility for the content of these articles. Please seek medical advice directly from your pharmacist or physician.
Copyright © 2024 HealthDay All Rights Reserved.